World J Mens Health.
2021 Oct;39(4):760-775. 10.5534/wjmh.200181.
Highly Cited Articles in the Field of Male Infertility and Antioxidants: A Scientometric Analysis
- Agarwal A
1 - Selvam MKP1
- Baskaran S1
- Finelli R1
- Leisegang K2
- Barbăroșie C3
- Pushparaj PN4,5
- Robert KA1
- Ambar RF6
- Iovine C7
- Durairajanayagam D8
- Henkel R1,9,10
- Affiliations
-
- 1American Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH, USA
- 2School of Natural Medicine, Faculty of Community and Health Sciences, University of the Western Cape, Bellville, South Africa
- 3Department of Genetics, Faculty of Biology, University of Bucharest, Bucharest, Romania
- 4King Abdulaziz University, Center of Excellence in Genomic Medicine, Jeddah, Saudi Arabia
- 5Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
- 6Urology Department of Centro Universitario em Saude do ABC/Andrology Group at Ideia Fertil Institute of Human Reproduction, Santo André, Brazil
- 7Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania Luigi Vanvitelli, Caserta, Italy
- 8Department of Physiology, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Selangor, Malaysia
- 9Department of Medical Bioscience, University of the Western Cape, Bellville, South Africa
- 10Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK
- KMID: 2519917
- DOI: http://doi.org/10.5534/wjmh.200181
Abstract
- Purpose
The objective of this scientometric analysis was to recognize the top 100 cited articles on ‘Male infertility and Antioxidants’ and analyze its publication characteristics.
Materials and Methods
The Scopus database was used to retrieve related articles and the top 100 identified based on citation rate.
Results
The articles were published in 56 journals between 1995 and 2019 with a median (interquartile range) citation score of 17 (5–62). Among the top 100 articles, 69 were clinical studies, which included controlled and blinded (33.33%), prospective (27.54%), randomized-controlled trials (26.09%), uncontrolled (11.59%), and retrospective (1.45%) studies. In addition to conventional semen parameters, advanced sperm function tests such as oxidative stress (51%) and sperm DNA damage (23%) were reported. Pregnancy rate (33%) was found to be the most reported reproductive outcome. Antioxidant therapy was mostly investigated in male cohorts with sperm abnormalities such as asthenozoospermia (28%) and clinical conditions such as idiopathic male infertility (20%), varicocele/varicocelectomy (17%) and general male infertility (16%).
Conclusions
The most influential publications on antioxidants and male infertility were identified for the first time in the literature. This will serve as a reliable source of information for researchers and clinicians alike.
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