J Korean Assoc Oral Maxillofac Surg.  2021 Aug;47(4):279-285. 10.5125/jkaoms.2021.47.4.279.

Comparative evaluation of the efficacy of wound healing with and without dehydrated human amniotic/chorionic membrane in alveoloplasty: a pilot study

• Gajul M
• Bhate K
• Awate S
• Kakodkar P
• Shah S

• KMID: 2519825
• DOI: http://doi.org/10.5125/jkaoms.2021.47.4.279

Abstract

Objectives
Wound healing is an integral part of any surgical procedure. Appropriate wound closure is critical to any successful surgical procedure, especially intraoral procedures. Various factors aid in wound healing, both pharmacological and non-pharmacological. Dehydrated human amniotic/ chorionic membrane (dHACM) is an emerging bioinert material that contains anti-inflammatory properties, angiogenetic properties, osteogenic potential, and various growth factors. The purpose of this study was to evaluate the efficacy of wound healing properties of dHACM in bilateral alveoloplasty patients.
Materials and Methods
A prospective split-mouth study was conducted on 10 patients. Site A received sutures with dHACM and site B was sutured without dHACM. Wound healing was assessed with the Landry, Turnbull, and Howley Index.
Results
Sites A and site B were compared. A P<0.05 and a test value of 22 was obtained, indicating a statistical difference between the two sites.
Conclusion
Our study showed better healing with dHACM than without.

Keyword

Biological dressings; Amnion; Wound Healing; Alveoloplasty