Korean J Urol Oncol.  2021 Aug;19(3):136-147. 10.22465/kjuo.2021.19.3.136.

Microbiome of Genitourinary Tumors: Especially in Prostate Cancer and Kidney Cancer

Affiliations
  • 1Department of Biomedical Science & Engineering, Gwangju Instititute of Science and Technology, Gwangju, Korea
  • 2Department of Urology, Chungbuk National Univesity College of Medicine, Cheongju, Korea
  • 3Department of Urology, Kyungpook National University Chilgok Hospital, Daegu, Korea
  • 4Department of Urology, School of Medicine, Kyungpook National University, Daegu, Korea

Abstract

Human body contains diverse microbes. Different microbes are identified at different organs. Urine was thought as sterile, but according to progression in important technologies like 16S rRNA gene sequencing and expanded quantitative urine culture, it is known that diverse microbes exist in genitourinary tract. Microbiome contains the microbes and surrounding microenvironments. In addition to urologic difficulties like interstitial cystitis or chronic prostatitis, malignancies are thought to be related to microbiomes. In this review, we summarized several studies in urologic malignancies, especially prostate cancer and kidney cancer.

Keyword

Microbiome, Prostate cancer, Kidney cancer, 16S rRNA
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