Korean J Gastroenterol.  2021 Aug;78(2):138-143. 10.4166/kjg.2021.044.

Pancreatic Acinar Cell Cystadenoma Mimicking Pancreatic Serous Cystadenoma

• Lee JH
• Jung SJ
• Park YH
• Park SJ
• Choi JS

• KMID: 2519383
• DOI: http://doi.org/10.4166/kjg.2021.044

Abstract

Acinar cell cystadenoma, also known as an acinar cystic transformation of the pancreas, is an exceedingly rare but benign pancreatic lesion. A 51-year-old woman was transferred to Inje University Busan Paik Hospital because of an 8 cm-sized calcified, multiseptated, and multilocular cystic mass in the pancreatic tail observed during abdominal CT performed at another hospital. The patient did not complain of abdominal pain or other symptoms, and her laboratory findings were normal. MRI showed that the cyst was not connected to the main pancreatic duct. A pancreatic serous cystadenoma was suspected, and a laparoscopic distal pancreatectomy was performed. The resected mass was composed of variable sized multilocular cysts with incomplete septa and focally lined by epithelium with acinar differentiation. The patient was diagnosed with acinar cell cystadenoma and is currently being followed up regularly. No complications or recurrences have been observed.

Keyword

Acinar cells; Cysts; Cystadenoma; Pancreas

Figure

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  Fig. 1 Abdominal computed tomography revealed an 8 cm-sized calcified, multiseptated, and multilocular cystic mass in the pancreatic tail (arrow).

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  Fig. 2 Pancreatic magnetic resonance imaging (T2-weighted axial image) revealed an 8 cm-sized lobulated multilocular cyst in the pancreatic tail (arrow).

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  Fig. 3 Distal pancreatectomy specimen showed well delineated mutilocular cystic mass measuring 7.0×4.0×3.0 cm (arrows indicate mass boundaries).

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  Fig. 4 (A) Microscopic findings revealed variable sized multilocular cysts with incomplete septa (H&E,×100), and (B) focally linned by epithelium with acinar differentiation (arrows) (H&E,×100).

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