Clin Orthop Surg.  2021 Sep;13(3):344-351. 10.4055/cios20175.

Platelet-Rich Plasma, Mesenchymal Stem Cell, and Non-metallic Suture-Based Fixation Technique in a Patellar Fracture Nonunion: A Technical Note and Systematic Review

Affiliations
  • 1Department of Orthopaedics and Traumatology, San Francesco d’Assisi Hospital, Oliveto Citra, Italy
  • 2Department of Musculoskeletal Disorders, Faculty of Medicine and Surgery, University of Salerno, Salerno, Italy
  • 3Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy
  • 4Centre for Sports and Exercise Medicine, Barts and The London School of Medicine and Dentistry, Mile End Hospital, Queen Mary University of London, London, England
  • 5School of Pharmacy and Bioengineering, Keele University Faculty of Medicine, Newcastle-under-Lyme, England

Abstract

Background
We performed a systematic review on the management of patellar fracture nonunion and report a novel suturebased non-metallic fixation technique associated with platelet-rich plasma and mesenchymal stem cell injections in the management of this injury.
Methods
A systematic search was performed up to August 2020 in PubMed and Scopus electronic databases of scholarly articles evaluating different surgical techniques used for nonunion of patellar fractures, with no restrictions on language or year of publication. Furthermore, we describe our novel non-metallic suture fixation technique and a patient in whom this technique was applied.
Results
A total of 9 articles were included in the systematic review. Tension band wiring was the most commonly used procedure (62.7%). Nonoperative procedures (8.1%) resulted in nonunion in all patients. The most common complication after open reduction and internal fixation was infection (7.8%). Our patient at the latest follow-up reported full functional recovery and full extension and flexion of the affected knee with no pain and subjectively normal strength.
Conclusions
The management of patella nonunions is still a challenge. The technique reported here can be used in patellar fracture nonunion, as well as in primary patellar fractures.

Keyword

Patella; Fracture; Non-union; Delayed union; Pseudarthrosis; Pseudoarthrosis
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