J Korean Neurol Assoc.
2021 Aug;39(3):192-196. 10.17340/jkna.2021.3.14.
Neuroleptic Malignant Syndrome Applied with Targeted Temperature Management
- Affiliations
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- 1Department of Neurology, Seoul National University Bundang Hospital, Seoul National University School of Medicine, Seongnam, Korea
- 2Division of Neurocritical Care, Department of Neurosurgery and Neurology, Seoul National University Bundang Hospital, Seoul National University School of Medicine, Seongnam, Korea
- KMID: 2518940
- DOI: http://doi.org/10.17340/jkna.2021.3.14
Abstract
- Neuroleptic malignant syndrome (NMS) is a life-threatening neurologic emergency associated with the use of dopamine receptor-antagonist properties or the rapid withdrawal of dopaminergic medications. NMS is characterized by refractory hyperpyrexia, altered mental state, dysautonomia, and rigor. If hyperpyrexia persists, it can result in multiorgan failure. Herein, we report a case of NMS occurring after metoclopramide administration in a patient with pontine hemorrhage, which was successfully treated with targeted temperature management using a surface cooling device.
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