J Korean Ophthalmol Soc.  2021 Jul;62(7):983-988. 10.3341/jkos.2021.62.7.983.

Chondroid Syringoma Involving the Sub-brow Area

Affiliations
  • 1Department of Ophthalmology, Pusan National University School of Medicine, Busan, Korea
  • 2Biomedical Convergence Research Institute, Pusan National University Hospital, Busan, Korea

Abstract

Purpose
Chondroid syringoma of the skin is a rare subcutaneous tumor and localization in the eyelid and orbital region that has rarely been described. We report a case of chondroid syringoma that involved the sub-brow region and was accompanied by hair loss.
Case summary
A 57-year-old women presented with a mass on the lateral side of the left sub-brow region which was observed 25 years earlier. The mass, which recurred 2 months after surgery at another hospital through a skin incision was accompanied by an itching sensation. The mass was not tender or ulcerated but was reddish with superficial blood vessels and had a smooth surface with hair loss at the site of the mass. The mass showed high signal intensity on a T2-weighted magnetic resonance image and a round echogenic nodule with an irregular hypoechoic portion was observed on ultrasonography. A full-thickness excision including the adjacent normal tissue of the sub-brow mass and direct closure were subsequently performed. The pathological diagnosis was chondroid syringoma which was revealed as numerous tubular structures with various lumens in a collagenous stroma. Mucinous and fibrous findings were also observed. No recurrence was detected during the first 2 years after surgery.
Conclusions
Chondroid syringoma in the eyelid and sub-brow region is uncommon. Complete resection is required to differentiate it from a malignancy and reduce the possibility of recurrence. Incomplete resection or capsular rupture during removal of the tumor could induce recurrence or a malignant change in the tumor.

Keyword

Chondroid syringoma, Eyelid mass, Mixed tumor, Sub-brow mass
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