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Cancer of the oral cavity and pharynx represents the 7th most diagnosed malignancy in Spain. Mucoepidermoid carcinomas are the most frequent malignancies of the minor salivary glands of oral cavities. The purpose of this report is to describe the very rare case of an alveolar ridge high-grade mucoepidermoid carcinoma presenting as an inside socket radiolucent lesion, simulating an apical cyst. The patient was diagnosed in our unit for oral and maxillofacial surgery and treated with surgery and adjuvant radiotherapy. The patient continues to be free of recurrent/persistent, local/regional disease after two years of follow up. Non-healed tooth related lesions present for more than one year are strongly recommended to be biopsied and evaluated histopathologically.
Fig. 1
Initial panoramic X-ray showing the radiolucent lesion (arrows) occupying the entire socket of mandibular left first molar.
Fig. 2
H&E staining (×1) photomicrograph showing the neoplasia forming solid nests, separated by fibroinflammatory stroma.
Fig. 3
Photomicrograph of the immunohistochemical analysis (×1) for P40 whose positivity in the nuclei confirmed the squamous-related origin of the tumor.
Fig. 4
Postsurgery panoramic X-ray showing the amplitude of the bone resection and the choice of reinforcement using a 2.0 reconstruction plate at the basal margin.
Fig. 5
Photomicrograph of the unitary lymph node metastasis (H&E staining, ×20).
10. Kolokythas A, Connor S, Kimgsoo D, Fernandes RP, Ord RA. 2010; Low-grade mucoepidermoid carcinoma of the intraoral minor salivary glands with cervical metastasis: report of 2 cases and review of the literature. J Oral Maxillofac Surg. 68:1396–9. https://doi.org/10.1016/j.joms.2009.12.019. DOI: 10.1016/j.joms.2009.12.019. PMID: 20363544. Article