Clin Exp Reprod Med.  2021 Jun;48(2):184-187. 10.5653/cerm.2020.04070.

Successful pregnancy following transmyometrial embryo transfer after robot-assisted radical trachelectomy

Affiliations
  • 1Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea
  • 2Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea

Abstract

Radical trachelectomy is a fertility-preserving alternative to radical hysterectomy in carefully selected young women with early-stage cervical cancer. However, in cases with subsequent severe cervical stenosis, assisted reproductive techniques can be difficult. This is a case report of a 34-year-old patient who underwent robot-assisted radical trachelectomy and cerclage for early-stage (IB2) adenosquamous carcinoma. Three months after surgery, the patient underwent ovarian stimulation using a gonadotropin-releasing hormone antagonist protocol. As it was impossible to perform transcervical embryo transfer due to the almost complete absence of the cervical opening, transmyometrial embryo transfer under ultrasound guidance was performed. This resulted in a successful singleton pregnancy. This is the first case of successful pregnancy conceived by in vitro fertilization with transmyometrial embryo transfer in a patient who had previously undergone robot-assisted radical trachelectomy.

Keyword

Embryo transfer; Fertility Preservation; Oocyte Retrieval; Trachelectomy; Uterine cervical Neoplasms
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