Tissue Eng Regen Med.  2021 Jun;18(3):327-341. 10.1007/s13770-021-00333-4.

Comparison of Autogenous Tooth Materials and Other Bone Grafts

  • 1Stomatological Materials Laboratory, School of Stomatology, Shandong First Medical University, Tai’an 271016, Shandong, China
  • 2Department of Oral and Maxillofacial Surgery, Graduate School of Clinical Dentistry, Korea University, Seoul 02841, Republic of Korea


Autogenous odontogenic materials are a new, highly biocompatible option for jaw restoration. The inorganic component of autogenous teeth acts as a scaffold to maintain the volume and enable donor cell attachment and proliferation; the organic component contains various growth factors that promote bone reconstruction and repair. The composition of dentin is similar to that of bone, which can be a rationale for promoting bone reconstruction. Recent advances have been made in the field of autogenous odontogenic materials, and studies have confirmed their safety and feasibility after successful clinical application. Autogenous odontogenic materials have unique characteristics compared with other bone-repair materials, such as the conventional autogenous, allogeneic, xenogeneic, and alloplastic bone substitutes. To encourage further research into odontogenic bone grafts, we compared the composition, osteogenesis, and development of autogenous odontogenic materials with those of other bone grafts. In conclusion, odontogenic bone grafts should be classified as a novel bone substitute.


AutoBT; Autograft; Bone reconstruction; Implant; Tooth material
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