Pediatr Gastroenterol Hepatol Nutr.  2021 May;24(3):316-324. 10.5223/pghn.2021.24.3.316.

Growth Patterns of Indonesian Infants with Cow's Milk Allergy and Fed with Soy-Based Infant Formula

• Setiabudiawan B
• Sitaresmi MN
• Sapartini G
• S
• Citraresmi E
• Sekartini R
• Putra AM
• Jo J

• KMID: 2515834
• DOI: http://doi.org/10.5223/pghn.2021.24.3.316

Abstract

Purpose
The use of soy-based infant formula has increased widely in infants with cow's milk allergy (CMA). This study aimed to provide evidence on the growth pattern of CMA infants fed with soy-based infant formula in an Indonesian setting.
Methods
A multi-site, intervention study was conducted among full-term and normal birth weight CMA infants. Within six months, the subjects were provided with a soy-based infant formula. Weight, height, and head circumference were measured at baseline, weeks 4, 8, 12, 16, 20, and 24. Adverse events were recorded by scoring atopic dermatitis and symptombased clinical scores.
Results
Based on the World Health Organization growth chart, we found that most of subjects had normal nutritional status for weight-for-age, length-for-age, weight-for-length, and head-circumference-for-age. There were statistically significant differences between baseline and end-line for weight-for-age, length-for-age, weight-for-length, and head circumference-for-age nutritional status. No allergic symptoms or intolerance toward soy formula were observed at the end of the intervention period.
Conclusion
These results show that infants fed with soy-based infant formula have a normal pattern of growth.

Keyword

Soy milk; Milk hypersensitivity; Body weight; Body height