Int J Gastrointest Interv.  2021 Apr;10(2):72-76. 10.18528/ijgii210004.

Percutaneous radiologic gastrostomy in patients with amyotrophic lateral sclerosis: A safe and effective technique

  • 1Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
  • 2Department of Interventional Therapy, National Cancer Center, National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China


Percutaneous radiologic gastrostomy (PRG) was considered as an alternative technique for long-term enteral nutrition, and the current study is aimed to evaluate the feasibility and safety of this technique in patients with amyotrophic lateral sclerosis (ALS) at a single medical center.
From July 2017 to October 2020, a total of 14 patients underwent PRG with ALS were included in this retrospective study with a median age of 64.0 years, and 78.6% were male. The procedure comprised a dilation of the stomach via a nasogastric catheter, followed by puncture and gastrostomy tube placement under fluoroscopic guidance. The technical success rate and clinical outcomes were recorded over 3 months following the procedure.
The technical success rate was 100%. During the follow-up period, minor complications were reported in 2 of patients (14.3%) including superficial skin infection and early tube block. Neither major complications nor mortality were observed. Body mass index of the patients increased significantly from 16.4 ± 2.1 kg/m 2 to 17.1 ± 2.0 kg/m2 (t = –13.77; P < 0.001), and the albumin level increased significantly from 37.5 ± 2.3 g/L to 41.8 ± 1.6 g/L (t = –8.82, P < 0.001).
PRG is a relatively safe and effective method for ALS patients, and deserves widespread clinical acceptance.


Amyotrophic lateral sclerosis; Deglutition disorders; Gastrostomy; Interventional radiology
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