Arch Craniofac Surg.
2021 Apr;22(2):71-77. 10.7181/acfs.2021.00080.
Effects of perioperative radiation treatment on stricture and fistula formation in hypopharyngeal reconstruction: a meta-analysis
- Affiliations
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- 1Department of Plastic and Reconstructive Surgery, Jeonbuk National University Medical School, Jeonju, Korea
- 2Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea
- 3Department of Radiation Oncology, Jeonbuk National University Medical School, Jeonju, Korea
- KMID: 2515405
- DOI: http://doi.org/10.7181/acfs.2021.00080
Abstract
- Hypopharyngeal reconstruction is a surgically challenging procedure, and postoperative management is important due to a high rate of complications following surgery. In particular, stricture and fistula formation is the most common long-term postoperative complication. Through systematic review and meta-analysis of 21 studies, a significant radiation effect of stricture and fistula formation was found in patients who underwent hypopharyngeal reconstruction. The perioperative radiation must be seen as a critical factor for stricture and fistula formation in hypopharyngeal reconstruction.
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