Korean J Radiol.
2021 May;22(5):677-687. 10.3348/kjr.2020.1166.
Breast Ultrasound Microvascular Imaging and Radiogenomics
- Affiliations
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- 1Department of Radiology, Bundang CHA Medical Center, CHA University, Seongnam, Korea
- 2Department of Radiology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea
- 3Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, Korea
- KMID: 2515056
- DOI: http://doi.org/10.3348/kjr.2020.1166
Abstract
- Microvascular ultrasound (US) techniques are advanced Doppler techniques that provide high sensitivity and spatial resolution for detailed visualization of low-flow vessels. Microvascular US imaging can be applied to breast lesion evaluation with or without US contrast agents. Microvascular US imaging without a contrast agent uses a sophisticated wall filtering system to selectively obtain low-flow Doppler signals from overlapped artifacts. Microvascular US imaging with secondgeneration contrast agents amplifies flow signals and makes them last longer, which facilitates hemodynamic evaluation of breast lesions. In this review article, we will introduce various microvascular US techniques, explain their clinical applications in breast cancer diagnosis and radiologic-histopathologic correlation, and provide a summary of a recent radiogenomic study using microvascular US.
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