J Korean Soc Radiol.
2021 Mar;82(2):423-428. 10.3348/jksr.2020.0106.
Progressive Transformation of Germinal Centers in Axillary Lymph Nodes Mimicking Metastatic Lymphadenopathy after Breast Cancer Surgery: A Case Report
- Affiliations
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- 1Department of Radiology, Korea University Anam Hospital, Seoul, Korea.
- 2Department of Radiology, Korea University Guro Hospital, Seoul, Korea.
- 3Department of Radiology, Korea University Ansan Hospital, Ansan, Korea.
- 4Department of Pathology, Korea University Anam Hospital, Seoul, Korea.
- KMID: 2514736
- DOI: http://doi.org/10.3348/jksr.2020.0106
Abstract
- Progressive transformation of germinal centers (PTGC) is a rarely diagnosed, benign disease of the lymph nodes that commonly manifests as chronic lymphadenopathy. PTGC may be characterized by single or multiple non-tender lymph nodes, and it commonly involves the cervical, axillary, and inguinal areas. Although PTGC is identified with concurrent lymphoma in some patients, it is not considered as a premalignant entity. Histopathologic diagnosis of PTGC is rarely made, and imaging findings have been reported in very few studies. We present a case of PTGC that occurred at the contralateral axillary lymph nodes and mimicked metastatic lymphadenopathy after breast cancer surgery. We also discuss its imaging findings.
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