Diabetes Metab J.  2020 Oct;44(5):679-686. 10.4093/dmj.2019.0125.

Deterioration of Sleep Quality According to Glycemic Status

• Hur MH
• Lee MK
• Seong K
• Hong JH

• KMID: 2513030
• DOI: http://doi.org/10.4093/dmj.2019.0125

Abstract

Type 2 diabetes mellitus (T2DM) is a progressive disease with multiple complications. The present study aimed to determine the effects of glycemic status on sleep quality in individuals with T2DM, prediabetes, and normal glucose tolerance (NGT).

A total of 90 participants were categorized into three groups, T2DM (n=30), prediabetes (n=30), and NGT (n=30). Objective sleep quality was measured with the actigraph wrist-worn device over 3 nights and subjective sleep quality was evaluated with a questionnaire.

The duration of diabetes in the T2DM group was 2.23 years and the glycosylated hemoglobin (HbA1c) levels in the T2DM, prediabetes, and NGT groups were 7.83%, 5.80%, and 5.31%, respectively. Sleep efficiency decreased across the T2DM, prediabetes, and NGT groups (86.25%, 87.99%, and 90.22%, respectively; P=0.047). Additionally, HbA1c levels revealed a significant negative correlation with sleep efficiency (r=−0.348, P=0.001). The sleep quality questionnaire results were similar among the three groups.

Although the participants in the present study were not necessarily conscious of their sleep disturbances, deterioration in sleep quality progressed according to glycemic status.

Keyword

Actigraphy; Diabetes mellitus, type 2; Glycated hemoglobin A; Prediabetic state; Sleep

Figure

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  Fig. 1 Study protocol (left image) and photo of the Actigraph device (Actigraph Corp.) on a wrist (right image). T2DM, type 2 diabetes mellitus; OGTT, oral glucose tolerance test; HbA1c, glycosylated hemoglobin; DM, diabetes mellitus.

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  Fig. 2 Sleep quality data acquired with the Actigraph (Actigraph Corp.) in the type 2 diabetes mellitus (T2DM), prediabetes, and normal glucose tolerance (NGT) groups; arrows indicate the sleep onset and wake up points (representative data of each group). EF, efficiency.

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