Korean J Head Neck Oncol.  2020 Nov;36(2):27-31. 10.21593/kjhno/2020.36.2.27.

IgG4 Related Disease Misdiagnosed to Carotid Body Tumor

Affiliations
  • 1Department of Otorhinolaryngology-Head & Neck Surgery, College of Medicine, Catholic Kwandong University
  • 2Department of Pathology, College of Medicine, Catholic Kwandong University

Abstract

Neck mass has various etiologies, including inflammatory, congenital, neoplastic causes. The IgG4-related disease can cause symptoms in the head and neck areas with an inflammatory neck mass. It also shows clinical and pathological findings from inflammation caused by immune reactions, such as lymphocyte and plasma cell infiltration, storiform fibrosis, obliteration phlebitis, and invigorated serum IgG4 levels. The treatment guideline has not been established and still under debate, but systemic glucocorticoid seems to be effective in the most cases. In this brief report, a 48-year-old male patient presented with voice change for 3 weeks. Left side paramedian vocal fold palsy was observed in the flexible laryngoscopy. About 2.5X2.0X1.2cm size, heterogeneously enhanced neck mass with irregular margin encasing left carotid artery was noted on preoperative contrast enhanced neck CT scan, and it was suspicious of left carotid body tumor. The pathology shows IgG4-related disease rather than carotid body tumors. We report this case of IgG4-related disease, which can be misdiagnosed to carotid body tumors.

Keyword

Carotid body tumor; IgG4-related disease; Neck mass; Vocal fold palsy
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