Korean J Med.  2021 Feb;96(1):30-35. 10.3904/kjm.2021.96.1.30.

Diagnosis and Treatment of Adult-Onset Still’s Disease

• Kim S
• Kim HR
• Lee SH
• Min HK

• KMID: 2512543
• DOI: http://doi.org/10.3904/kjm.2021.96.1.30

Abstract

Adult-onset Still’s disease (AOSD) is an obscure disease that is usually diagnosed after the exclusion of other febrile diseases, including other autoimmune, infectious, and malignant diseases. Although definitive diagnostic criteria and treatment guidelines for AOSD are thus far lacking, the typical manifestations of AOSD have been identified and effective medications for remission and maintenance have been proposed. The pathophysiology of the AOSD is unclear, but diagnostic criteria and treatment guidelines for AOSD can be established by determining its core etiology and conducting clinical trials of previously tested immunosuppressants and biologics.

Keyword

Still's disease, adult-onset; Physiopathology; Therapy; 성인형 스틸병; 병인; 치료