Nat Prod Sci.
2020 Dec;26(4):334-339. 10.20307/nps.2020.26.4.334.
Lanostane Triterpenoids from Ganoderma tropicum Collected in Vietnam and Their Nitroblue Tetrazolium Reductive Activity In Vitro
- Affiliations
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- 1National Institute of Medicinal Materials (NIMM), 3B Quang Trung, Hoan Kiem dist., Ha Noi, Vietnam
- 2Institute of Drug Quality Control Ho Chi Minh City, 200 Co Bac Str., Ward Co Giang, District 1, Ho Chi Minh City, Vietnam
- 3National Institute of Drug Quality Control, 48 Hai Ba Trung str., Hoan Kiem, Ha Noi, Vietnam
- KMID: 2511960
- DOI: http://doi.org/10.20307/nps.2020.26.4.334
Abstract
- A new compound, 3β-acetoxylanosta-7,9(11),24-triene-26-al (3), and seven known compounds (1 – 2 and 4 – 8) were isolated from Ganoderma tropicum (Jung.) Bres. collected in Tay Nguyen, Vietnam. The structures of these compounds were determined by one- and two-dimensional nuclear magnetic resonance spectroscopy, electrospray ionization mass spectrometry (ESI-MS), and high-resolution ESI-MS, and by comparison with literature data. All of the isolated compounds were tested for nitroblue tetrazolium (NBT) reduction activity in Saccharomyces cerevisiae-stimulated RAW 246.7 cells. Among them, compounds 2 – 4 and 6 – 8 enhanced the NBT reduction in a dose-dependent manner.
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