J Korean Ophthalmol Soc.  2020 Dec;61(12):1493-1499. 10.3341/jkos.2020.61.12.1493.

Factors Affecting Intraocular Pressure after Laser Iridotomy in Fellow Eye with Acute Angle Closure Glaucoma

• Kim YM
• Kim DW

• KMID: 2511291
• DOI: http://doi.org/10.3341/jkos.2020.61.12.1493

Abstract

Purpose
To investigate the factors affecting intraocular pressure (IOP) change after prophylactic laser iridotomy (LI) in the fellow eye with acute angle closure glaucoma.
Methods
Twenty-three subjects with acute primary angle closure glaucoma, who had undergone prophylactic LI in the fellow eye were enrolled in this study. IOP was measured before and 1 week after prophylactic LI. Compared with a week after and before the prophylactic LI, eleven eyes with the IOP reduction of 20% or more were classified into A group and twelve eyes with an IOP reduction of 20% or less were classified as B group. Anterior segment parameters were measured using anterior segment swept source optical coherence tomography.
Results
The mean age, the best corrected visual acuity, the baseline IOP and the axial length were not significantly different between the two groups (p > 0.05). The IOP after prophylactic LI was significantly different between the two groups (group A 11.36 ± 1.96 mmHg, Group B 13.50 ± 1.83 mmHg; p = 0.013). There was a significant difference in IOP change rate of the two groups (Group A 29.78 ± 11.09%, Group B 9.14 ± 5.91%; p < 0.001). In multiple regression analysis, only the anterior chamber depth was significantly associated with the IOP change rate (p = 0.011).
Conclusions
The anterior chamber depth is associated with the change of IOP after prophylactic LI in the fellow eye with acute primary angle closure glaucoma. If the anterior chamber depth is shallow, it is highly likely that the change of IOP is relatively small. Therefore, the anterior chamber depth must be considered in assessing the effectiveness of prophylactic LI.

Keyword

Acute angle closure glaucoma; Anterior chamber depth; Prophylactic laser iridotomy