J Korean Ophthalmol Soc.  2020 Dec;61(12):1450-1457. 10.3341/jkos.2020.61.12.1450.

Incidence and Risk Factors of Epiretinal Membrane Following Acute Posterior Vitreous Detachment

• Lee SJ
• Oh JH

• KMID: 2511286
• DOI: http://doi.org/10.3341/jkos.2020.61.12.1450

Abstract

Purpose
To investigate the incidence and risk factors of epiretinal membrane (ERM) after acute posterior vitreous detachment (PVD).
Methods
We reviewed the medical records of patients diagnosed with PVD between February 2013 and February 2019. Patients with symptom onset (new floaters or photopsia) within 1 month at the time of diagnosis were included in the study. The ERM was diagnosed using fundus photographs. The incidence rate was investigated in each of the three periods: 1-3, 3-6, and 6-12 months after symptom onset. The cumulative incidence rate of ERM was calculated using Kaplan-Meier analysis. Data were analyzed using logistic regression to determine the association between ERM development and various factors.
Results
The study included 154 eyes. The mean age was 56.6 ± 8.0 years. ERM was observed in three of 144 eyes (2.1%) between 1 month and 3 months, in 11 of 56 eyes (19.6%) between 3 and 6 months, and in 15 of 63 eyes (23.8%) between 6 and 12 months from symptom onset. The cumulative incidence rate of ERM was 35.3% over the 12 months following the onset of PVD symptoms. In a multivariate logistic regression analysis, the fellow eye with ERM (odds ratio 11.9, 95% confidence interval 1.4-100.1) was significantly associated with ERM development.
Conclusions
ERM development was relatively common after PVD. Long-term follow-up of 6 months or more should be required after the onset of symptoms.

Keyword

Epiretinal membrane; Incidence; Posterior vitreous detachment; Risk factor