Clin Exp Emerg Med.  2020 Dec;7(4):250-258. 10.15441/ceem.20.035.

Outcome and status of postcardiac arrest care in Korea: results from the Korean Hypothermia Network prospective registry

Affiliations
  • 1Department of Emergency Medicine, Eunpyeong St. Mary’s Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea
  • 2Department of Emergency Medicine, Seoul St. Mary’s Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea
  • 3Department of Emergency Medicine, Ajou University Medical Center, Suwon, Korea
  • 4Department of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
  • 5Department of Emergency Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea
  • 6Department of Emergency Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea
  • 7Department of Emergency Medicine, Daegu Catholic University Medical Center, Catholic University of Daegu School of Medicine, Daegu, Korea
  • 8Department of Emergency Medicine, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Korea
  • 9Department of Emergency Medicine, Ewha Womans University Mokdong Hospital, Ewha Womans School of Medicine, Seoul, Korea
  • 10Department of Emergency Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
  • 11Department of Emergency Medicine, Hanil General Hospital, Seoul, Korea
  • 12Department of Emergency Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea
  • 13Department of Emergency Medicine, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, Seoul, Korea
  • 14Department of Emergency Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea
  • 15Department of Emergency Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
  • 16Department of Emergency Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea
  • 17Department of Emergency Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
  • 18Department of Emergency Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea
  • 19Department of Emergency Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea
  • 20Department of Emergency Medicine, St. Vincent’s Hospital, The Catholic University of Korea College of Medicine, Suwon, Korea
  • 21Department of Emergency Medicine, Uijeongbu St. Mary’s Hospital, The Catholic University of Korea College of Medicine, Uijeongbu, Korea
  • 22Department of Emergency Medicine, Yeouido St. Mary’s Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea
  • 23Department of Emergency Medicine, Wonju Severance Christian Hospital, Yonsei University College of Medicine, Wonju, Korea

Abstract


Objective
High-quality intensive care, including targeted temperature management (TTM) for patients with postcardiac arrest syndrome, is a key element for improving outcomes after out-of-hospital cardiac arrest (OHCA). We aimed to assess the status of postcardiac arrest syndrome care, including TTM and 6-month survival with neurologically favorable outcomes, after adult OHCA patients were treated with TTM, using data from the Korean Hypothermia Network prospective registry.
Methods
We used the Korean Hypothermia Network prospective registry, a web-based multicenter registry that includes data from 22 participating hospitals throughout the Republic of Korea. Adult comatose OHCA survivors treated with TTM between October 2015 and December 2018 were included. The primary outcome was neurological outcome at 6 months.
Results
Of the 1,354 registered OHCA survivors treated with TTM, 550 (40.6%) survived 6 months, and 413 (30.5%) had good neurological outcomes. We identified 839 (62.0%) patients with preClinsumed cardiac etiology. A total of 937 (69.2%) collapses were witnessed, shockable rhythms were demonstrated in 482 (35.6%) patients, and 421 (31.1%) patients arrived at the emergency department with prehospital return of spontaneous circulation. The most common target temperature was 33°C, and the most common target duration was 24 hours.
Conclusion
The survival and good neurologic outcome rates of this prospective registry show great improvements compared with those of an earlier registry. While the optimal target temperature and duration are still unknown, the most common target temperature was 33°C, and the most common target duration was 24 hours.

Keyword

Out-of-hospital cardiac arrest; Hypothermia, induced; Registries; Critical care outcomes
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