Korean J Dermatol.  2020 Nov;58(9):617-619.

A Case of Poromatosis Related to Chemotherapy

• Kim Ya
• Ha DL
• Son JH
• Shin Kh
• Lee Js
• Kim HS
• Ko HC
• Kim BS
• Kim MB

Abstract

A poroma is a benign adnexal neoplasm originating from the sweat gland duct. It usually presents clinically as a soft erythematous or flesh-colored papule, plaque, or nodule on the palms and soles. In most cases, poromas manifest as a solitary lesion, but rarely, multiple lesions have been reported and are defined as poromatosis. Although the pathogenesis is unclear, poromatosis is known to be associated with actinic damage, human papillomavirus infection, radiation therapy, or polychemotherapy. Herein, we describe a 53-year-old woman who had multiple erythematous papules on her feet for a year. She had a medical history of acute lymphoblastic leukemia and had undergone polychemotherapy with stem cell transplantation. To our knowledge, poromatosis related to chemotherapy is a rare entity, and our case could be attributed to the theory that using polychemotherapy can induce poromatosis.

Keyword

Chemotherapy; Leukemia; Poroma; Poromatosis