J Korean Neurosurg Soc.  2020 Nov;63(6):814-820. 10.3340/jkns.2020.0139.

Clinical Outcome of Percutaneous Trigeminal Nerve Block in Elderly Patients in Outpatient Clinics

Affiliations
  • 1Department of Neurosurgery, School of Medicine, Kyung Hee University, Seoul, Korea

Abstract


Objective
: Trigeminal neuralgia (TN) is a severe neuropathic condition that affects several elderly patients. It is characterized by uncontrolled pain that significantly impacts the quality of life of patients. Therefore, the condition should be treated as an emergency. In the majority of patients, pain can be controlled with medication; however, other treatment modalities are being explored in those who become refractory to drug treatment. The use of the trigeminal nerve block with a local anesthetic serves as an excellent adjunct to drug treatment. This technique rapidly relieves the patient of pain while medications are being titrated to effective levels. We report the efficacy and safety of percutaneous trigeminal nerve block in elderly patients with TN at our outpatient clinic.
Methods
: Twenty-one patients older than 65 years with TN received percutaneous nerve block at our outpatient clinic. We used bupivacaine (1 mL/injection site) to block the supraorbital, infraorbital, superior alveolar, mental, and inferior alveolar nerves according to pain sites of patients.
Results
: All patients reported relief from pain, which decreased by approximately 78% after 2 weeks of nerve block. The effect lasted for more than 4 weeks in 12 patients and for 6 weeks in two patients. There were no complications.
Conclusion
: Percutaneous nerve block procedure performed at our outpatient clinic provided immediate relief from pain to elderly patients with TN. The procedure is simple, has no serious side effects, and is easy to apply.

Keyword

Trigeminal neuralgia; Nerve block; Bupivacaine; Emergency

Figure

  • Fig. 1. Score after treatment of each patient.

  • Fig. 2. Score after treatment of each branch of trigeminal nerve. N : nerve, Sup. : superior, Inf. : inferior.


Reference

References

1. Amirnovin R, Neimat JS, Roberts JA, Eskandar EN. Multimodality treatment of trigeminal neuralgia. Stereotact Funct Neurosurg. 83:197–201. 2005.
Article
2. Arıcı T, Kurcaloğlu M, Kılıç E, Erhan E. Radiofrequency thermocoagulation combined with pulsed radiofrequency for gasserian ganglion blockage. Agri. 30:179–182. 2018.
Article
3. Ashkan K, Marsh H. Microvascular decompression for trigeminal neuralgia in the elderly: a review of the safety and efficacy. Neurosurgery. 55:840–848. discussion 848-850. 2004.
Article
4. Bahgat D, Ray DK, Raslan AM, McCartney S, Burchiel KJ. Trigeminal neuralgia in young adults. J Neurosurg. 114:1306–1311. 2011.
Article
5. Bertilsson L. Clinical pharmacokinetics of carbamazepine. Clin Pharmacokinet. 3:128–143. 1978.
Article
6. Dach F, Éckeli ÁL, Ferreira Kdos S, Speciali JG. Nerve block for the treatment of headaches and cranial neuralgias - a practical approach. Headache 55 Suppl. 1:59–71. 2015.
Article
7. Emril DR, Ho KY. Treatment of trigeminal neuralgia: role of radiofrequency ablation. J Pain Res. 3:249–254. 2010.
8. Fernandez C, Reader A, Beck M, Nusstein J. A prospective, randomized, double-blind comparison of bupivacaine and lidocaine for inferior alveolar nerve blocks. J Endod. 31:499–503. 2005.
Article
9. Fraioli MF, Cristino B, Moschettoni L, Cacciotti G, Fraioli C. Validity of percutaneous controlled radiofrequency thermocoagulation in the treatment of isolated third division trigeminal neuralgia. Surg Neurol. 71:180–183. 2009.
Article
10. Hascalovici JR, Robbins MS. Peripheral nerve blocks for the treatment of headache in older adults: a retrospective study. Headache. 57:80–86. 2017.
Article
11. Hong T, Ding Y, Yao P. Long-term efficacy and complications of radiofrequency thermocoagulation at different temperatures for the treatment of trigeminal neuralgia. Biochem Res Int. 2020:3854284. 2020.
Article
12. Ilfeld BM. Continuous peripheral nerve blocks: a review of the published evidence. Anesth Analg. 113:904–925. 2011.
13. Ilfeld BM, Viscusi ER, Hadzic A, Minkowitz HS, Morren MD, Lookabaugh J, et al. Safety and side effect profile of liposome bupivacaine (exparel) in peripheral nerve blocks. Reg Anesth Pain Med. 40:572–582. 2015.
Article
14. Kanpolat Y, Savas A, Bekar A, Berk C. Percutaneous controlled radiofrequency trigeminal rhizotomy for the treatment of idiopathic trigeminal neuralgia: 25-year experience with 1,600 patients. Neurosurgery. 48:524–532. discussion 532-534. 2001.
Article
15. Maarbjerg S, Di Stefano G, Bendtsen L, Cruccu G. Trigeminal neuralgia - diagnosis and treatment. Cephalalgia. 37:648–657. 2017.
Article
16. Maarbjerg S, Heinskou TB, Wolfram F, Rochat P, Brennum J, Bendtsen L. Diagnostics and treatment of trigeminal neuralgia. Ugeskr Laeger. 178:V02160146. 2016.
17. Marchetti M, Pinzi V, De Martin E, Ghielmetti F, Fariselli L. Radiosurgery for trigeminal neuralgia: the state of art. Neurol Sci. 40(Suppl 1):153–157. 2019.
Article
18. Marshall K, Chan MD, McCoy TP, Aubuchon AC, Bourland JD, McMullen KP, et al. Predictive variables for the successful treatment of trigeminal neuralgia with gamma knife radiosurgery. Neurosurgery. 70:566–572. discussion 572-573. 2012.
Article
19. Oomens MA, Forouzanfar T. Pharmaceutical management of trigeminal neuralgia in the elderly. Drugs Aging. 32:717–726. 2015.
Article
20. Perloff MD, Chung JS. Urgent care peripheral nerve blocks for refractory trigeminal neuralgia. Am J Emerg Med. 36:2058–2060. 2018.
Article
21. Sarsam Z, Garcia-Fiñana M, Nurmikko TJ, Varma TR, Eldridge P. The long-term outcome of microvascular decompression for trigeminal neuralgia. Br J Neurosurg. 24:18–25. 2010.
Article
22. Stienen MN, Cadosch D, Seule MA, Fournier JY, Hildebrandt G, Gautschi OP. Trigeminal neuralgia - pathophysiology, clinical aspects and treatment. Praxis (Bern 1994). 99:29–43. 2010.
23. Wilkinson HA. Trigeminal nerve peripheral branch phenol/glycerol injections for tic douloureux. J Neurosurg. 90:828–832. 1999.
Article
24. Xia L, Zhong J, Zhu J, Wang YN, Dou NN, Liu MX, et al. Effectiveness and safety of microvascular decompression surgery for treatment of trigeminal neuralgia: a systematic review. J Craniofac Surg. 25:1413–1417. 2014.
Article
25. Yadav YR, Nishtha Y, Sonjjay P, Vijay P, Shailendra R, Yatin K. Trigeminal neuralgia. Asian J Neurosurg. 12:585–597. 2017.
Article
Full Text Links
  • JKNS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr