J Korean Neurosurg Soc.  2020 Nov;63(6):784-793. 10.3340/jkns.2020.0013.

Change of Pyogenic and Tuberculous Spondylitis between 2007 and 2016 Year : A Nationwide Study

Affiliations
  • 1Department of Neurosurgery, Bundang CHA Medical Center, CHA University College of Medicine, Seongnam, Korea
  • 2Department of Neurosurgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
  • 3Department of Neurosurgery, Cheongju St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Cheongju, Korea
  • 4Department of Public Health Science, Graduate School of Public Health, Seoul National University, Seoul, Korea
  • 5Department of Medical Device Management and Research, SAIHST, Sungkyunkwan University, Seoul, Korea

Abstract


Objective
: We attempted to compare the incidence of pyogenic spondylitis (PS) and tuberculous spondylitis (TS) between 2007 and 2016. Furthermore, we investigated the patients who underwent surgery in 2016 compared to that in 2007.
Methods
: We used a nationwide database managed by the Korean National Health Insurance Service (NHIS) in 2007 and 2016. Total 9655 patients with a newly diagnosis of PS or TS were enrolled in PS or TS group. Among them, 1721 patients underwent either fusion or decompression surgery. We analyzed demographic distribution of patients according to gender and age and year of diagnosis.
Results
: Comparing between 2007 and 2016, the incidence of PS has increased in 2016 than in 2007 (4874 vs. 2431, p<0.0001). Conversely, declination of incidence of TS was discovered in 2016 compared to 2007 (594 vs. 1756, p<0.0001). Females showed predominance over males regarding both PS and TS (5228 vs. 4427, p<0.0001). Among them, the number of PS patients who underwent surgery increased significantly in 2016 relative to that in 2007 (979 vs. 592, p<0.0001).
Conclusion
: This nationwide study suggests that PS may increase and TS may decrease in Korea. In addition, demand for surgery regarding PS may increase.

Keyword

Nationwide study; Pyogenic spondylitis; Tuberculosis, Spinal; Epidemiology; Infectious spondylitis

Figure

  • Fig. 1. Flow for establishment of this nationwide study. Among the patients with pyogenic spondylitis (PS) and tuberculous spondylitis (TS) (n=13277), patients with previous diagnosis of the diseases within 1 year was excluded. Subsequently, patients under 20 years old were excluded followed by exclusion of patients diagnosed as both diseases.

  • Fig. 2. Comparison of the incidence of PS and TS in 2007 and 2016. A : The incidence of PS was significantly higher in 2016 compared to in 2007. B : The incidence of TS outnumbered in 2007 relative to in 2016 (P<0.0001). PS : pyogenic spondylitis, TS : tuberculous spondylitis.


Reference

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