Int J Arrhythm.  2020 Jun;21(2):e8. 10.1186/s42444-020-00016-6.

The relationship between J wave and ventricular tachycardia during Takotsubo cardiomyopathy

  • 1Division of Cardiology, Department of Internal Medicine, Inha University College of Medicine and Inha University Hospital, 27 Inhang‑ro, Jung‑gu, Incheon 22332, Republic of Korea


Background and objectives
Takotsubo cardiomyopathy (TTC) occasionally causes life-threatening ventricular arrhythmia. J wave on surface electrocardiography (sECG) has also been associated with idiopathic ventricular fibrillation and cardiac events; therefore, we investigated whether the presence of J wave on sECG is a potential risk factor for ventricular arrhythmia in patients with TTC.
Subjects and methods
We performed a retrospective study in 79 patients who were diagnosed with TTC from 2010 to 2014. Among them, 20 (25.3%) were diagnosed with ventricular tachycardia (VT). The J wave on the sECG was defined as J point elevation manifested through QRS notching or slurring at least 1 mm above the baseline in at least two leads.
A higher prevalence of ventricular tachycardia was observed in patients with J wave. The corrected QT interval (QTc) was significantly longer in the VT group than in the non-VT group. In a multivariate analysis, the presence of J wave appeared to be the only independent predictors of VT [Hazard Ratio (HR) 3.5, p = 0.019].
Our results suggest that the presence of J wave on the sECG is significantly associated with VT, and appear to indicate that the presence of J wave is a strong and independent predictor of VT in patients with TTC.


J wave; Ventricular tachycardia; Takotsubo cardiomyopathy
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