Ann Dermatol.  2020 Oct;32(5):426-429. 10.5021/ad.2020.32.5.426.

A Case of Pseudomyogenic Hemangioendothelioma of the Lower Extremity

• Choi ME
• Lim DJ
• Chang SE
• Lee MW
• Choi JH
• Lee WJ

• KMID: 2506996
• DOI: http://doi.org/10.5021/ad.2020.32.5.426

Abstract

Pseudomyogenic hemangioendothelioma (PMH) is a rare vascular tumor and was recently recognized as a distinct entity. It has a predilection for young male adults and it frequently occurs in distal extremities. Although it is known to follow an indolent course, multi-focal presentation and local recurrence are common. PMH should be differentiated from epithelioid sarcoma, epithelioid hemangioendothelioma, dermatofibrosarcoma protuberans, and rhabdomyosarcoma. Its characteristic immunohistochemical staining pattern and recurrent translocation t(7:19)(q22:q13) are the basis for its diagnosis. Surgical excision is the mainstay treatment, although chemotherapy can be considered in non-operable patients. We present a rare case of a 40-year-old Korean male patient diagnosed with PMH through an excisional biopsy to facilitate the recognition PMH in the clinical practice.

Keyword

Epithelioid cells; Hemangioendothelioima; Leg; Soft tissue neoplasms