Ann Clin Microbiol.  2020 Sep;23(3):209-213. 10.5145/ACM.2020.23.3.4.

Isolation of Carnobacterium divergens from Blood Culture in Korea : A Case Report and Literature Review

Affiliations
  • 1Department of Laboratory Medicine, Dong-A University School of Medicine, Busan, Korea

Abstract

Carnobacterium is a genus of gram-positive bacilli belonging to the family Lactobacillaceae. Generally, Carnobacterium species are considered nonpathogenic to humans and are mostly found in the natural environment, food, and food packaging. Furthermore, some Carnobacterium species play a bioprotective role in the food industry. Isolation of Carnobacterium from human blood or other sites, such as skin or abscess, has rarely been reported—there are only four published case reports worldwide, and none of them is from Korea. In all the reported cases, the patients reported contact with an aqueous environment or were administered nutrition via a parenteral route. Herein, we report the detection of Carnobacterium divergens bacteremia in an immunocompromised patient by using mass spectrometry in Korea.

Keyword

Blood cultures; Carnobacterium divergens; MALDI-ToF/MS

Figure

  • Fig. 1. Carnobacterium divergens on the surface of sheep blood agar after a two day cultivation at 37°C.

  • Fig. 2. Gram staining of Carnobacterium divergens observed on microscopy (×1,000)


Reference

1. Xu J, Yang H, Lai X, Fu X, Wu J, Huang L, et al. Etiological study for a case of multi-bacterial synergistic gangrene. Chinese Sci Bull 1997;42:511-7.
2. Chemelar D, Matusek A, Korger J, Durnova E, Steffen M, Chmelarova E. Isolation of Carnobacterium piscicola from human pus – case report. Folia Microbiol 2002;47:455-7.
3. Leisner JJ, Laursen BG, Prevost H, Drider D, Dalgaard P. Carnobacterium: positive and negative effects in the environment and in foods. FEMS Microbiol Rev 2007;31:592-613.
4. Hoenigl M, Grisold AJ, Valentin T, Leitner E, Zarfel G, Renner H, et al. Isolation of Carnobacterium sp. from a human blood culture. J Med Microbiol 2010;59:493-5.
5. Carbonnelle E, Mesquita C, Bille E, Day N, Dauphin B, Veretti JL, et al. MALDI-TOF mass spectrometry tools for bacterial identification in clinical microbiology laboratory. Clin Biochem 2011;44:104-9.
6. Smati M, Palacios C, Cohen Y, Mechai F, Tankovic J, Fleche-Mateos A, et al.Carnobacterium divergens bacteremia in woman. Emerg Infect Dis 2015;21:1081.
7. Danielski GM, Imazaki PH, Andrade Cavalari CM, Daube G, Clinquart A, Freitas de Macedo RE. Carnobacterium maltomaticum as bioprotective culture in vitro and in cooked ham. Meat Sci 2020;162:108035.
8. Schillinger U and Holzapfel WH. The genus Carnobacterium. In: Wood BJB, Holzapfel WH, eds. The genera of lactic acid bacteria. Vol 2, Boston; Springer, 1995:307-26.
9. Scarpellini M, Mora D, Colombo S, Franzetti L. Development of genus/species-specific PCR analysis for identification of Carnobacterium strains. Curr Microbiol 2002;45:24-9.
10. Barakat RK, Griffiths MW, Harris LJ. Isolation and characterization of Carnobacterium, Lactococcus, and Enterococcus spp. from cooked, modified atmosphere packaged, refrigerated, poultry meat. Int J Food Microbiol 2000;62:83-94.
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