J Korean Ophthalmol Soc.  2020 Aug;61(8):950-954. 10.3341/jkos.2020.61.8.950.

Blepharoptosis Secondary to Local Conjunctival and Tarsal Amyloidosis

• Choi HJ
• Son BJ

• KMID: 2505316
• DOI: http://doi.org/10.3341/jkos.2020.61.8.950

Abstract

Purpose
To report a case of primary conjunctival and tarsal amyloidosis with blepharoptosis.
Case summary
A 73-year-old woman presented with left blepharoptosis and foreign body sensation that worsened over a1-year period prior. She presented with severe blepharoptosis on the left upper lid, with slightly reduced levator function. Duringthe operation, a fragile yellowish-pink mass-lesion was observed, widely involving palpebral conjunctiva and the space betweenthe levator aponeurosis and tarsal plate. While levator resection was withheld, the mass was excised as much as possible andblepharoplasty was performed. After surgery, the blepharoptosis improved slightly, and histopathologic examination revealedamyloid deposits. Because there were no abnormal findings in systemic examinations including blood tests, chest X-rays, andabdominal ultrasonography, the patient was diagnosed as primary conjunctival and tarsal amyloidosis.
Conclusions
Although local amyloidosis of the conjunctiva and tarsal plate is rare, it should be considered in differential diagnosisof patients with involutional blepharoptosis.

Keyword

Blepharoptosis; Conjunctival & tarsal amyloidosis