J Korean Soc Biol Ther Psychiatry.  2020 Jun;26(2):88-100.

A Review of Clinical Applications of Hyperbaric Oxygen Therapy in Psychiatric Disorders

Affiliations
  • 1Ewha Brain Institute, Ewha W. University, Seoul
  • 2Graduate School of Pharmaceutical Sciences, Ewha W. University, Seoul
  • 3Department of Brain and Cognitive Sciences, Ewha W. University, Seoul

Abstract

Hyperbaric oxygen therapy (HBOT) is a noninvasive method that supplies pure oxygen under a pressure greater than normal atmospheric pressure to increase the partial pressure of oxygen in the plasma and tissue. Based on the potential mechanisms of HBOT, including neuroprotection and neurological recovery, HBOT has been suggested as a promising therapeutic option for neurological and psychiatric disorders. This review specifically focused on the clinical trials applying HBOT for psychiatric disorders published during the recent decade. We critically reviewed the efficacy and safety of HBOT in psychiatric disorders, and cautiously suggested the future directions for further research.

Keyword

Hyperbaric oxygenation; Mental disorders; Treatment outcome; Safety
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