Korean J Med.  2020 Jun;95(3):211-215. 10.3904/kjm.2020.95.3.211.

A Fatal Pulmonary Event during Plasma Exchange in a Patient with Severe Fever with Thrombocytopenia Syndrome

Affiliations
  • 1Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea
  • 2Department of Laboratory Medicine, Jeju National University School of Medicine, Jeju, Korea

Abstract

Severe fever with thrombocytopenia syndrome (SFTS) caused by the SFTS virus (SFTSV), a novel Phlebovirus, is endemic to South Korea, central and northeastern China, and western Japan. SFTS poses a threat to public health because of its high mortality and secondary transmission. Ticks and domestic animals are hosts for SFTSV in endemic areas. There is no specific treatment for SFTS, and avoiding tick bites is the best way to prevent infection. Early therapeutic plasma exchange (TPE) is a rescue therapy in patients with rapidly progressive SFTS. Here, we present a patient with SFTS who was improving on TPE but died suddenly due to acute lung injury after TPE.

Keyword

중증 열성혈소판감소증후군; 혈장교환술; 폐부종; Severe fever with thrombocytopenia syndrome; Plasma exchange; Pulmonary edema
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