J Mov Disord.
2020 May;13(2):159-162. 10.14802/jmd.20005.
Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
- Lombardo M
1,2 - DiPiazza A1,2
- Rippey K3
- Lubarr N4
- Clar E2,4
- Azmi H1,2
- Affiliations
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- 1Department of Neurosurgery, Hackensack University Medical Center, Hackensack, NJ, USA
- 2North Jersey Brain and Spine Center, Hackensack, NJ, USA
- 3Division of Trauma and Critical Care, Department of Surgery, Hackensack University Medical Center, Hackensack, NJ, USA
- 4Department of Neurology, Hackensack University Medical Center, Hackensack, NJ, USA
- KMID: 2503084
- DOI: http://doi.org/10.14802/jmd.20005
Abstract
- The treatment of delirium or psychosis in patients with Parkinson’s disease (PD) can be complicated by the limited number of pharmacological agents that can be used in this population. Typical and atypical antipsychotics are contraindicated, as they can worsen motor symptoms. The treatment of acute delirium is even more complicated in the hospital setting, as many medications deemed safer in this population are only available in oral form. We present a case of acute delirium in a patient with PD, likely precipitated by a polypharmacy interaction of new medications, that was successfully managed by transferring the patient to the intensive care unit and administering dexmedetomidine for 72 hours.
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