J Korean Orthop Assoc.  2020 Jun;55(3):237-243. 10.4055/jkoa.2020.55.3.237.

Effect of Postoperative Parathyroid Hormone Administration on Osteoporotic Intertrochanteric Fractures of Females

• Oh HC
• Yoo JH
• Ha JW
• Park Y
• Park SH
• Yoon HK

• KMID: 2502618
• DOI: http://doi.org/10.4055/jkoa.2020.55.3.237

Abstract

Purpose
This study examined the effects of the postoperative administration of parathyroid hormone (PTH) on fracture healing in intertrochanteric fractures accompanied by osteoporosis in elderly females.
Materials and Methods
Female patients aged 65 years and more who underwent surgery after a diagnosis of intertrochanteric fractures and osteoporosis during the period from July 2013 to December 2017 were included as subjects. The subjects were divided into two groups: PTH-treated group and non-PTH-treated group. The formation time of the first callus, timing of the bridging callus, and time of bony union for both groups were evaluated.
Results
In the PTH-treated group, the mean time of the first callus formation, average time of bridging callus, and the average time of bony union were 32, 58, 83 days, respectively, which were significantly shorter than that of the untreated group.
Conclusion
PTH, a treatment for osteoporosis, promotes callus formation and the healing process. Therefore it will be helpful in intertrochanteric fractures accompanied by osteoporosis in elderly females.

Keyword

femur; osteoporosis; parathyroid hormone