Pediatr Gastroenterol Hepatol Nutr.  2020 May;23(3):286-296. 10.5223/pghn.2020.23.3.286.

Quality of Life in Children and Adolescents with Inflammatory Bowel Disease: Impact and Predictive Factors

• Silva LC
• Seixas RBM
• Carvalho Ed

• KMID: 2502497
• DOI: http://doi.org/10.5223/pghn.2020.23.3.286

Abstract

Purpose
Inflammatory bowel disease (IBD) in children and adolescents is associated with high morbidity and possibly has a significant negative impact on their quality of life. This study aimed to evaluate the quality of life of children and adolescents with IBD and define the variables that impact these individuals.
Methods
We administered the Pediatric Quality of Life Questionnaire (PedsQL) to 35 children and adolescents diagnosed with IBD and with available quantitative data from clinical records on epidemiology, clinical evolution, complementary tests, medical interventions, and disease activity. Data were evaluated according to the IBD type and compared with a control group of healthy children.
Results
The study group showed a significantly lower PedsQL score than the control group (p<0.01). Significant factors contributing to poor overall quality of life included female sex, Crohn's disease, surgery, and food restrictions. Symptoms such as diarrhea and the fear of using public toilets were associated with low physical scores. Feeling sick had a negative impact on the emotional PedsQL scores. Patients with a fear of using public toilets, anthropometric scores below the 3rd percentile, and greater disease activity scored lower in the social domain. Regarding school and psychosocial evaluations, younger children with symptom onset after the age of 2 years had lower scores than younger children with symptom onset before the age of 2 years.
Conclusion
IBD negatively affects the quality of life of children and adolescents based on its impact on the physical, emotional, social, and psychosocial statuses of these patients.

Keyword

Inflammatory bowel disease in pediatrics; Health-related quality of life; Pediatric Quality of Life Questionnaire 4.0 Generic Core Scale questionnaire