Korean J Intern Med.  2020 Jan;35(1):41-59. 10.3904/kjim.2019.411.

The use of biological disease-modifying antirheumatic drugs for inflammatory arthritis in Korea: results of a Korean Expert Consensus

• Park EJ
• Kim H
• Jung SM
• Sung YK
• Baek HJ
• Lee J

• KMID: 2501985
• DOI: http://doi.org/10.3904/kjim.2019.411

Abstract

Biological disease-modifying antirheumatic drugs (bDMARDs) are highly effective agents for the treatment of inf lammatory arthritis; however, they also possess a potential risk for serious infection. Recently, with the rapid expansion of the bDMARDs market in Korea, reports of serious adverse events related to the agents have also increased, necessitating guidance for the use of bDMARDs. Current work entitled, “Expert consensus for the use of bDMARDs drugs for inflammatory arthritis in Korea,” is the first to describe the appropriate use of bDMARDs in the management of inflammatory arthritis in Korea, with an aim to provide guidance for the local medical community to improve the quality of clinical care. Twelve consensus statements regarding the use of bDMARDs for the management of rheumatoid arthritis and ankylosing spondylitis were generated. In this review, we provide detailed guidance on bDMARDs use based on expert consensus, including who should prescribe, the role of education, indications for use, and monitoring strategies for safety.

Keyword

Expert consensus; Biological disease-modifying antirheumatic drugs; Inflammatory arthritis; Arthritis, rheumatoid; Spondylitis, ankylosing