J Pathol Transl Med.  2020 Mar;54(2):188-191. 10.4132/jptm.2019.09.07.

Tumor-to-tumor metastasis: metastatic invasive lobular carcinoma of the breast within adenocarcinoma of the lung

• Kang MJ
• An AR
• Chung MJ
• Kim KM

• KMID: 2501610
• DOI: http://doi.org/10.4132/jptm.2019.09.07

Figure

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  Fig. 1. High resolution view of computed tomography scan shows pulmonary mass (arrow). The mass is located at right lower lobe of the lung and shows ground glass opacity.

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  Fig. 2. Histologic features of the breast needle biopsy and resected lung mass. (A) The tumor cells of the breast mass are arranged in infiltrating single linear cords. (B) Scan view of the pulmonary mass shows dimorphic growth pattern (circular area vs. other region). (C) Higher magnification of the circular area of Fig. 2B. The tumor cells are arranged in compact trabecular pattern with minimal cytoplasm. (D) Other region of the lung mass showing typical acinar growth pattern. The tumor cells of the circular area of panel B are negative for thyroid transcription factor-1 (E) and E-cadherin (F) and positive for estrogen (G) and progesterone receptor (H).

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