J Korean Orthop Assoc.  1975 Dec;10(4):438-441. 10.4055/jkoa.1975.10.4.438.

Multicentric Osteogenic Sarcoma: Report of a Case

Affiliations
  • 1Department of Orthopedic Surgery, Capital Armed Forces General Hospital, Seoul, Korea.

Abstract

We have experienced a case of very rare malignant tumor. multicentric osteogenic sarcoma, in which abnormalities were found radiologically in the body of second thoracic vertebrae, distal end of left femur, and simultaneous extraosseous lesion in the right infra-auricular region. The lesions were highly osteoblastic and rapidly growing. There were on secondary metastasis in the lungs. but regional lymph node metastasis were proved histopathologically.


MeSH Terms

Femur
Lung
Lymph Nodes
Neoplasm Metastasis
Osteoblasts
Osteosarcoma*
Thoracic Vertebrae

Figure

  • Fig 1. Α-P, lateral views of left fem jrå Highly osteoblastic and abundant tumor tissue involving the distal end of femur.

  • Fig. 2. Α-P, laterol views of left femur, 1 month laterå Remarkable enlargement of tumor mass.

  • Fig 3. Ρ -A view of chest; Osteoblastic tumor infiltration in the right half of Th-2 spine. No lung metastasis.

  • Fig. 4. P-Α view of thoracic spineå Close up view of tumorinfiltration of Th-2 spine.

  • Fig. 5. Α-P view of mandibleå Irregu larly lobu- lated calcific mass in the soft tissue space of right infra-auricular region. No bone changes

  • Fig. 6. Low power view of the neoplasm, showingæ deposition of osteoid. H & Ε Χ100.

  • Fig. 7. High power view of Fig. 6ô showing; pleomorphic tumor cells with osteoid formation. Η & Ε Χ 450.


Reference

1.Ackerman A. J.Multiple Osteogenic Sarcoma. Reports of two cases,. Am. J. Roentgenol. 60:623. 1948.
2.안화용, 정인환. 多生性骨肉腫: 一例報告. 中央醫學. 22:205. 1972.
3.Das Guptz T.K.., Hajdu S.I.., Foote F. W. Jr.Extraosseovs Osteogenic Sarcoma. Ann. Surg. 168:1011. 1968.
4.Durham A.E.Trans. Path. Soc. Lond. 34:265. 1883.
5.Edeiken J.., Hodes P.T.Roentgen Diagnosis of Diseases of Bone. 2nd ed.Williams and Wilkins Co. Baltimore;1973.
6.Jaffe H.L.Tumors & Tumorous Conditions of the Bones and Joints, lea and Febiger Philadelphia. 1968.
7.Kaity Y.., Bom A.F.., Griffithe C.O.., Grikeair G.F.Osteosarcoma Arising in Fibous Dysplasia of the Facial Bone. Am. J. of Surgery. 107:1964.
8.Lichtenstein L.Bone Tumors. St. Louis C. V. Mosby Co;1972.
9.Luck J.B.J.B.J.S. 39-A:757. 1957. (Discussion of paper by Coventry & Dahlin).
10.Marcove R.C.., Mike Y.., Hajek J.V.Osteogenic Sarcoma under the Age of 21. J.B. J.S. 52A:411. 1970.
11.Martland H.S.., Colon P.., Knee J.P.Some Unrecognized Danger in the use of Radioactive Substance, with Especial Reference of the Storage of Insoluble Product of Radium and Mesotherium in the Reticuloendothelial System. J. J. of Am. Med. Asso. 85:1968. 1925.
12.Mckenna R.J.., Schwinn C.P.., Soong K.Y.Sarcoma of the Osteogenic Series. J.B.J.S. 48 A:1. 1966.
13.Moseley J.E.., Bass M.H.Sclerosing Osteogenic Sarcomatosis: A Radiologic entity. Radiology. 96:41. 1956.
14.Owen L.H.An Account of Multiple Osteosarcomaa of Bone in Dogs Having Multicentric or Metastatic Origin, Brit. J. J. Radiol. 38:520. 1965.
15.Price C. H.G.Osteogenic Sarcoma. An Analysis of Survival and Its Relationship to Histological Grading and Structure,. J. J.B.J.S. 43-B:300. 1961.
16.Price C.H.G.., Truscott D.E.Multifocal Osteogenic Sarcoma. Report of A Case. J.B.J.S. 39-B-.524. 1957.
17.Ross F. G.M.Osteogenic Sarcoma. Brit. J. Radiolo. 37:259. 1964.
18.Ryan J.A Case of Multiple Osteosarcoma. J. Coll Radiol. Ausi. 7/2: 93. 1963.
19.Silverman G.Multple Osteogenic Sarcoma,. Arch., Path. 21:88. 1936.
20.宋文甲, 徐源赫, 李道行. 朴诱誠: 多生性骨肉腫와'“-例:: 大韓放射線醫學會雜誌. 3:51. 1967.
21.Willis R. A.The spread of Tumorin the Human Body. Lodon. P. 325, 1934. Quated by Finlay son, R.: Osteogenic of Path, and Bad. 66:223. 1953.
Full Text Links
  • JKOA
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr