J Korean Clin Nurs Res.  2019 Dec;25(3):251-264. 10.22650/JKCNR.2019.25.3.251.

A Meta-Analysis on Factors Related to Quality of Life in Heart Transplant Recipients

• Jang MR
• Im SR
• Choi M

• KMID: 2470640
• DOI: http://doi.org/10.22650/JKCNR.2019.25.3.251

Abstract

PURPOSE
This study was a systematic review and meta-analysis to explore the factors related to quality of life in heart transplant recipients.
METHODS
To identify studies that suggested the factors related to the quality of life in heart transplant recipients, we searched the articles published from 1974 to November 2018 using Six databases, PubMed, CINAHL, EMBASE, Cochrane, KMBASE and RISS. A total of 22 studies were selected out of 5,234 for the systematic review and meta-analysis on the basis of the PRISMA flow. The quality of study was assessed by assessment tool form the NIH and meta-analysis was performed using the "˜R 3.5.2' version to analyze the correlated effect sizes.
RESULTS
Factors related to quality of life in heart transplant recipients were categorized into six domains based on the health-related quality of life model introduced by Ferrans: individual, environmental, biological function, symptoms, functional status, and general health perception. In the meta-analysis, 34 factors were used and 17 factors having significant effect sizes were as follows: self-efficacy, demoralization, perceived control, current occupational status, age, marital status, health promotion life style in the individual characteristics; stress in environmental characteristics; physical function status, creatinine level, left ventricular ejection fraction (LVEF) in biological function; anxiety, depression, symptom frequency and distress in symptoms domain; coping, self-care compliance in functional status.
CONCLUSION
The findings indicate that the multi-dimensional factors influencing the quality of life in heart transplant recipients and provide the evidence for developing effective interventions for improving the quality of life of recipients.

Keyword

Heart Transplantation; Quality of Life; Systematic Review; Meta-Analysis

MeSH Terms

Anxiety
Compliance
Creatinine
Depression
Employment
Health Promotion
Heart Transplantation
Heart*
Life Style
Marital Status
Quality of Life*
Self Care
Stroke Volume
Transplant Recipients*
Creatinine