Korean J Helicobacter Up Gastrointest Res.  2019 Sep;19(3):156-160. 10.7704/kjhugr.2019.19.3.156.

Endoscopic Treatment for Esophageal Cancer

• Gong EJ
• Kim DH

• KMID: 2469328
• DOI: http://doi.org/10.7704/kjhugr.2019.19.3.156

Abstract

Although surgical resection is the mainstay of treatment for resectable esophageal cancer, it is associated with considerable morbidity and mortality. Endoscopic resection, including endoscopic mucosal resection and endoscopic submucosal dissection, has been considered as a feasible alternative to surgical resection for superficial esophageal squamous cell carcinoma based on its minimal invasiveness and favorable outcomes in suitable indications. The long-term outcomes of endoscopic resection are comparable to those of surgery when tumors are confined to the intraepithelial or lamina propria layer because these tumors have low or no risk of lymph node metastasis. The results of histopathological examination of the resected specimens should be interpreted thoroughly regarding the requirement of additional treatment. Treatment-related adverse events include bleeding, perforation, and stricture. Preventive measures should be taken during and after the procedure, particularly when the mucosal defects account for more than three-fourths of the circumference. In this review, the indications and outcomes of endoscopic treatment for esophageal squamous cell carcinoma are summarized.

Keyword

Endoscopic mucosal resection; Endoscopic submucosal dissection; Esophageal neoplasms

MeSH Terms

Carcinoma, Squamous Cell
Constriction, Pathologic
Esophageal Neoplasms*
Hemorrhage
Lymph Nodes
Mortality
Mucous Membrane
Neoplasm Metastasis