Korean J Helicobacter Up Gastrointest Res.  2019 Dec;19(4):277-281. 10.7704/kjhugr.2019.0018.

Gastric Ulcers with Cytomegalovirus Infection in an Immunocompetent Patient

Affiliations
  • 1Department of Internal Medicine, Ewha Medical Research Institute, Ewha Womans University College of Medicine, Seoul, Korea. shimkn@ewha.ac.kr

Abstract

Cases of cytomegalovirus (CMV) infection are rare, and this infection is commonly asymptomatic in immunocompetent patients. Here, we report a pathologically proven case of CMV infection in gastric ulcers in an immunocompetent patient. A 35-year-old man visited our hospital for a surveillance esophagogastroduodenoscopy. Except fatigue, he had no other symptoms. Laboratory data showed that his white cell count was 9.28×10³/µL with 60.1% lymphocytes. However, aspartate transaminase and alanine aminotransferase levels were elevated. Esophagogastroduodenoscopy revealed multiple gastric ulcers that were healing. Two endoscopic biopsies were performed to obtain specimens at the ulcer base. Histological examination and immunohistochemistry confirmed CMV infection; subsequently, we decided that the best option was observation without medication. He revisited a month later, and the ulcers had disappeared.

Keyword

Cytomegalovirus; Immunocompetence, Stomach ulcer

MeSH Terms

Adult
Alanine Transaminase
Aspartate Aminotransferases
Biopsy
Cell Count
Cytomegalovirus Infections*
Cytomegalovirus*
Endoscopy, Digestive System
Fatigue
Humans
Immunohistochemistry
Lymphocytes
Stomach Ulcer*
Ulcer
Alanine Transaminase
Aspartate Aminotransferases
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