J Vet Sci.  2020 Jan;21(1):e1. 10.4142/jvs.2020.21.e1.

Preputial gland adenoma in a wild nutria (Myocastor coypus): a case report

• Kong JY
• Kim HS
• Yeon SC
• Park JK
• Jeong KS
• Hong IH

• KMID: 2469016
• DOI: http://doi.org/10.4142/jvs.2020.21.e1

Abstract

Tumor incidence in wild mammals is reportedly very low. Wild nutria, a large rodent, is known to carry many infectious diseases, but rarely exhibits neoplastic diseases. We necropsied a male wild nutria and found a large nodular mass in the left inguinal region, adjacent to the penis. Histopathologically, the mass was diagnosed as preputial gland adenoma. Spontaneous preputial gland adenomas are extremely rare in all animals. Moreover, reports of tumors in nutrias have been limited to adenocarcinomas of the lungs and uterus, as well as subcutaneous fibromas. Here, we describe preputial gland adenoma in a wild nutria.

Keyword

Adipophilin; nutria; preputial gland; sebaceous glands

MeSH Terms

Adenocarcinoma
Adenoma*
Animals
Communicable Diseases
Fibroma
Humans
Incidence
Lung
Male
Mammals
Penis
Rodentia
Sebaceous Glands
Uterus

Figure

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  Fig. 1. Necropsy of a male wild nutria. (A) The ventral aspect of the animal. The ventral skin has been peeled back, revealing a large muscle-covered mass (asterisk) lateral to the penis (arrow). (B) Cut surface of the mass. Yellowish exudates are observed.

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  Fig. 2. Microscopic examination of the mass in a male wild nutria. (A) The mass is composed of reserved basal cells and secretory cells containing oily and waxy matter, which constitute a type of sebaceous gland. The gland has a long excretory duct with a wide lumen lined by hyperplastic squamous epithelium. (B, C) The tumor cells have a central round nucleus with one or (rarely) 2 large nucleoli. The cytoplasm contains small to large vacuoles. (D) Adipophilin is expressed in intracytoplasmic lipid vacuoles in sebaceous cells. Hematoxylin and eosin (A-C); immunohistochemistry of adipophilin (D) (all scale bar = 100 µm).

Reference

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