Clin Exp Otorhinolaryngol.  2013 Sep;6(3):184-186.

Primary Burkitt's Lymphoma in the Nasal Cavity and Paranasal Sinuses

• Lee DH
• Yu MS
• Lee BJ

Abstract

Burkitt's lymphoma is a highly aggressive small B-cell lymphoma. The treatment of choice is complex chemotherapy. As a rare tumor in the head and neck area, Burkitt's lymphoma usually involves cervical lymph nodes, and only fewer than 25% of cases involves extranodal regions. Involvement of the paranasal sinuses has been reported in only 14 cases in the past century. We describe here two patients with rare, sporadic, American type Burkitt's lymphoma involving the nasal cavity and paranasal sinuses manifesting nasal obstruction. We also review clinical and histological features of Burkitt's lymphoma.

Keyword

Lymphoma; Burkitt lymphoma; Nasal cavity; Paranasal sinus

MeSH Terms

Burkitt Lymphoma
Head
Humans
Lymph Nodes
Lymphoma
Lymphoma, B-Cell
Nasal Cavity
Nasal Obstruction
Neck
Paranasal Sinuses

Figure

• 

  Fig. 1 Endoscopic findings, showing (A) a pinkish round mass originating from the middle meatus of the right nasal cavity, and (B) an irregularly contoured mass between the septum and inferior turbinate of the left nasal cavity.

• 

  Fig. 2 Axial and coronal view of sinus magnetic resonance imaging (T1WI), showing (A, B) opacification, mainly involving the right maxillary sinus and parapharyngeal and buccal spaces, before chemotherapy; (C, D) disappearance of previously observed mass lesions after chemotherapy, with only postoperative changes remaining.

Reference

1. Chen DT, Chen PR, Hsu LP, Chiu TJ, Hsu YH. Burkitt's lymphoma in paranasal sinuses. Otolaryngol Head Neck Surg. 2006; 12. 135(6):991–993. PMID: 17141106.

2. Nikgoo A, Mirafshariyeh SA, Kazeminajad B, Eshkevari PS, Fatemitabar SA. Burkitt's lymphoma of maxillary sinuses: review of literature and report of bilateral case. J Oral Maxillofac Surg. 2009; 8. 67(8):1755–1763. PMID: 19615595.

3. Lewis WB, Perlman PW, Ilasi J. Pediatric American Burkitt's lymphoma of the sphenoid sinus. Otolaryngol Head Neck Surg. 2000; 11. 123(5):642–644. PMID: 11077358.

4. Liang CW, Li HY, Chang KP, Chen CK, Chen YL. HIV infection initially presenting as sinonasal Burkitt's lymphoma. Am J Otolaryngol. 2006; Nov-Dec. 27(6):433–435. PMID: 17084232.

5. Ferry JA. Burkitt's lymphoma: clinicopathologic features and differential diagnosis. Oncologist. 2006; 4. 11(4):375–383. PMID: 16614233.