Psychiatry Investig.  2019 Dec;16(12):954-957. 10.30773/pi.2019.0116.

Combined Measures of Psychomotor and Cognitive Alterations as a Potential Hallmark for Bipolar Depression

• Robin A
• Sauvaget A
• Deschamps
• Bulteau S
• Thomas-Ollivier V

• KMID: 2467301
• DOI: http://doi.org/10.30773/pi.2019.0116

Abstract

OBJECTIVE
The current study aimed to examine whether specific features of psychomotor retardation (PMR) and cognitive functioning established different profiles in unipolar (UD) and bipolar depression (BD).
METHODS
Two groups of age-matched patients with UD (n=54) and BD (n=20) completed the Montgomery-Asberg Depression Rating Scale (MADRS/60), the Montreal Cognitive Assessment (MoCA/30), and the Salpêtrière Retardation Rating Scale (SRRS/60). We analyzed the group effect and then performed intra-group analyses.
RESULTS
The BD patients have higher SRRS score, and lower MoCA score than UD despite no difference on the level of depression between UD and BD. Our results show that PMR can be predicted by the level of depression in UD and by the cognitive alteration and onset of disease in BD.
CONCLUSION
PMR is a relevant marker of depression. Our results highlight the importance of concomitant evaluation of psychomotor and cognitive functions in the distinction of UD and BD symptoms.

Keyword

Psychomotor retardation; Unipolar depression; Bipolar depression; Cognitive functions

MeSH Terms

Bipolar Disorder*
Cognition
Depression
Depressive Disorder
Humans
Methylenebis(chloroaniline)
Methylenebis(chloroaniline)