J Korean Med Sci.  2019 Dec;34(50):e322. 10.3346/jkms.2019.34.e322.

The Trend in Incidence and Case-fatality of Hospitalized Acute Myocardial Infarction Patients in Korea, 2007 to 2016

Affiliations
  • 1Regional Cardiocerebrovascular Disease Center, Gyeongsang National University Hospital, Jinju, Korea.
  • 2Center of Biomedical Data Science, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 3Department of Precision Medicine & Biostatistics, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 4Department of Health Policy and Hospital Management, Graduate School of Public Health, Korea University, Seoul, Korea.
  • 5Department of Neurology, Gyeongsang Institute of Health, Gyeongsang National University School of Medicine, Jinju, Korea.
  • 6Department of Internal Medicine, Gyeongsang Institute of Health, Gyeongsang National University School of Medicine, Jinju, Korea. jyhwang@gnu.ac.kr

Abstract

BACKGROUND
The trend in the incidence of hospitalized acute myocardial infarction (AMI) and the difference between regions has not been reported in Korea since 2010. Thus, we aimed to inspect recent trends and regional differences in the incidence of AMI and case-fatality between 2007 and 2016.
METHODS
Data from the medical utilization cohort from 2002 to 2016 were analyzed. New incidence of AMI was identified by checking the diagnosis code, duration of admission, type of test, treatment, and medication. Age-standardized incidence rate by gender, age group, and resident region was calculated from 2007 to 2016. Cumulative case-fatality rate was calculated until 3 years.
RESULTS
Age-standardized incidence of hospitalized AMI decreased from 53.6 cases per 100,000 person-years in 2007 to 38.9 cases in 2011. Thereafter, the incidence gradually increased to 43.2 cases in 2016. The trend by gender and age groups was also similar to the total trend. The regional age-standardized incidence was the highest in Daegu (50.3 cases per 100,000 person-years) and the lowest in Sejong (30.2 cases), which were similar to the ischemic heart disease mortality in these regions. The 7-, 30-, and 90-days and 1- and 3-years average case-fatality over 10 years were 3.2%, 6.9%, 9.9%, 14.7%, and 22.4%, respectively.
CONCLUSION
Although case-fatality continuously decreased from 2007 to 2016, hospitalized AMI incidence decreased from 2007 to 2011 and gradually increased from 2011 to 2016, with marked disparity between regions. Effective preventive strategies to decrease AMI incidence are required to decrease cardiovascular disease mortality in Korea.

Keyword

Acute Myocardial Infarction; Incidence Rate; Case-Fatality; Regional Differences

MeSH Terms

Cardiovascular Diseases
Cohort Studies
Daegu
Diagnosis
Humans
Incidence*
Korea*
Mortality
Myocardial Infarction*
Myocardial Ischemia
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