Korean J Dermatol.
2019 Nov;57(9):544-547.
Eruptive Keratoacanthoma en Plaque Confirmed by Complete Spontaneous Regression: A Case Report and Review of the Literature
- Affiliations
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- 1Dapartment of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea.
- 2Dapartment of Pathology, Kyungpook National University School of Medicine, Daegu, Korea.
- 3Department of Dermatology, Daegu Catholic University Medical Center, Daegu, Korea.
- 4Institute of Medical Mycology, Catholic Skin Clinic, Daegu, Korea.
- 5Department of Pathology, Keimyung University School of Medicine, Daegu, Korea. hwlee@dsmc.or.kr
Abstract
- Here we present a case of an unusual variant of keratoacanthoma, eruptive keratoacanthoma en plaque, occurring on the upper lip of a 58-year-old man. The lesion was a flesh-colored nodular plaque measuring 1.5×1.0 cm that rapidly grew within 2 months. After two biopsies, the cutaneous lesion grew more rapidly for 1 month, covering the entire cutaneous surface of the upper lip and measuring 6.0×2.0 cm. Thereafter, it disappeared without any treatment within 3 months, resulting in mild scarring with a cobblestone-like surface similar to the stereotypical involuting course of ordinary keratoacanthoma. In addition to the clinical features, the present case displayed essential diagnostic features of eruptive keratoacanthoma by showing typical spontaneous involution not reported in previous reports. Furthermore, it also revealed histopathology suggestive of squamous cell carcinoma, at least focally in addition to that of keratoacanthoma, which may evoke the potential for a misdiagnosis of malignancy.
