Ann Surg Treat Res.  2019 Dec;97(6):296-301. 10.4174/astr.2019.97.6.296.

Frey's procedure for chronic pancreatitis: a 10-year single-center experience in Korea

• Kim HS
• Lee JH
• Park JS
• Yoon DS

• KMID: 2464785
• DOI: http://doi.org/10.4174/astr.2019.97.6.296

Abstract

PURPOSE
Chronic pancreatitis (CP) is progressive inflammatory disease that leads to irreversible destruction of the pancreatic parenchyma. The main indications for surgical intervention in cases involving CP are intractable pain, suspicion of malignancy, and failure of other methods. However, there is no report related to Frey's procedure in Korea; hence, we aimed to investigate and analyze our institution's experience and determine the benefits of surgical treatment for CP.
METHODS
This was a retrospective study of 24 patients with CP who underwent Frey's procedure at Gangnam Severance Yonsei University between January 2007 and December 2017. Preoperative exocrine and endocrine pancreatic function, perioperative finding (blood loss, operation time), postoperative complications were evaluated. Statistical analytics were chi-square test, Fisher exact tests, and Wilcoxon signed-rank test and Mann-Whitney U-test.
RESULTS
Surgery was performed due to alcohol-derived CP in 12 of 24 patients (50%) and due to pancreatic stones in 15 of 24 patients (62.5%). Two patients had postoperative complications which were managed conservatively. After surgery, 7 of 24 patients were prescribed with exocrine medication. Comparison of the preoperative and postoperative conditions showed that glycated hemoglobin had no significant differences. After surgery, only 5 patients (21%) complained of intermittent abdominal pain.
CONCLUSION
In conclusion, Frey's procedure appears to be a less burdensome surgical procedure. Thus, it could be the first option for management of patients with large pancreatic stone.

Keyword

Chronic pancreatitis; Pancreaticojejunostomy; Patient outcome

MeSH Terms

Abdominal Pain
Hemoglobin A, Glycosylated
Humans
Korea*
Pain, Intractable
Pancreaticojejunostomy
Pancreatitis, Chronic*
Postoperative Complications
Retrospective Studies

Figure

• 

  Fig. 1 Several large stones within main pancreatic duct in abdomen pelvic CT scan. (A) Pancreas Stone. (B) Preoperative CT scan. (C) Frey's procedure. The main pancreatic duct was opened. (D)Longitudinal side-toside pancreaticojejunostomy.

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