Ann Dermatol.  2019 Dec;31(6):685-686. 10.5021/ad.2019.31.6.685.

A Case of Recalcitrant Erythema Nodosum Associated with Pancreatic Cancer

• Jung IS
• Yun SJ
• Lee JB
• Lee SC
• Won YH

• KMID: 2461996
• DOI: http://doi.org/10.5021/ad.2019.31.6.685

Abstract

No abstract available.

MeSH Terms

Erythema Nodosum*
Erythema*
Pancreatic Neoplasms*

Figure

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  Fig. 1 Erythematous subcutaneous nodules on the right leg at first visit (A), 4 weeks (B), and 6 weeks later (C). The skin lesions aggravated despite intensive therapy including oral colchicines, analgesics, and oral steroid. We received the patient's consent form about publishing all photographic materials.

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  Fig. 2 Skin biopsy form leg nodule revealed fibrous interlobular septum with widening and septal infiltrate by inflammatory cells, including histiocytes, lymphocytes, and eosinophils. The infiltrate extends into adjacent fat lobules (H&E: A, scanning view; B, ×100; C, ×200).

Reference

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3. Virshup AM, Sliwinski AJ. Polyarthritis and subcutaneous nodules associated with carcinoma of the pancreas. Arthritis Rheum. 1973; 16:388–392.

4. Durden FM, Variyam E, Chren MM. Fat necrosis with features of erythema nodosum in a patient with metastatic pancreatic carcinoma. Int J Dermatol. 1996; 35:39–41.

5. Arbeláez-Cortés A, Vanegas-García AL, Restrepo-Escobar M, Correa-Londoño LA, González-Naranjo LA. Polyarthritis and pancreatic panniculitis associated with pancreatic carcinoma: review of the literature. J Clin Rheumatol. 2014; 20:433–436.