J Korean Ophthalmol Soc.  2019 Oct;60(10):990-993. 10.3341/jkos.2019.60.10.990.

Eyelid Myxoma in Carney Syndrome

Affiliations
  • 1Department of Ophthalmology, Chungnam National University College of Medicine, Daejeon, Korea. sblee@cnu.ac.kr

Abstract

PURPOSE
To report a case of eyelid myxoma in Carney syndrome.
CASE SUMMARY
A 24-year-old male presented with a 4-year history of a slowly growing nodule at the right upper eyelid. The patient underwent surgical excision five times for the eyelid nodule, which recurred at the same site. He was diagnosed with Carney syndrome. The eyelid lesion was pinkish and lobulated, and the surface was firm and soft. The nodule was completely excised and a histopathological examination revealed a myxoid matrix containing spindle- or stellate-shaped cells and many thin-walled vessels. The nodule was diagnosed as myxoma. There was no recurrence at 13 months after surgery.
CONCLUSIONS
Myxoma rarely involves the eyelid, but it should be considered in the differential diagnosis of multiple recurrent nodules of the eyelid. Complete excision is important if clinically suspected, and regular follow-up is needed after surgery. In addition, a thorough systemic evaluation, including echocardiography, should be performed to find any evidence of Carney syndrome.

Keyword

Carney complex; Myxoma

MeSH Terms

Carney Complex*
Diagnosis, Differential
Echocardiography
Eyelids*
Follow-Up Studies
Humans
Male
Myxoma*
Recurrence
Young Adult

Figure

  • Figure 1 Preoperative photographs. (A, B) Right eyelid showing 3.0 × 2.0 × 1.0 mm sized, pinkish, polypoid, firm, smooth surface, non-tender mass arising from the upper eyelid margin.

  • Figure 2 Histopathological images. (A) Ill-defined myxoid matrix containing spindle or stellate-shaped cells and many thin-walled vessels in the dermis (Hematoxylin-Eosin [H & E stain], ×100). (B) Spindle or stellate-shaped cells without atypia or mitotic figures in the myxoid stroma (H & E stain, ×400).


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