J Korean Ophthalmol Soc.  2019 Oct;60(10):953-958. 10.3341/jkos.2019.60.10.953.

Risk Factors that Affects Progression of Type 2 Retinopathy of Prematurity

• Han GH
• Chang JW

• KMID: 2460513
• DOI: http://doi.org/10.3341/jkos.2019.60.10.953

Abstract

PURPOSE
To identify risk factors that affect the development of type 2 retinopathy of prematurity (ROP) and progression to type 1 or threshold ROP requiring treatment.
METHODS
The medical records of premature infants born with a birth weight ≤1,500 g or a gestational age ≤32 weeks were retrospectively reviewed. Potential risk factors were divided into systemic and ophthalmic factors and analyzed by univariate and multivariate logistic regression analyses.
RESULTS
Three hundred and twenty-four eyes met the screening criteria. Among them, 41 eyes (12.65%) progressed to type 2 ROP and 21 eyes (6.48%) received treatment after progression to type 1 or threshold ROP. The systemic risk factor associated with progression from type 2 ROP was periventricular leukomalacia and the ophthalmic factor was the existence of nasal ROP at the time of diagnosis of type 2 ROP.
CONCLUSIONS
Careful examination was needed when type 2 ROP with periventricular leukomalacia or nasal ROP developed because there was a high probability of progression and treatment.

Keyword

Retinopathy of prematurity; Risk factors; Type 2 retinopathy of prematurity

MeSH Terms

Birth Weight
Diagnosis
Gestational Age
Humans
Infant, Newborn
Infant, Premature
Leukomalacia, Periventricular
Logistic Models
Mass Screening
Medical Records
Retinopathy of Prematurity*
Retrospective Studies
Risk Factors*

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