Perinatology.  2019 Sep;30(3):134-139. 10.14734/PN.2019.30.3.134.

Comparison of Bilirubin Levels in Neonates with Hyperbilirubinemia according to Delivery Methods

• Lee GY
• Choi JW

• KMID: 2460026
• DOI: http://doi.org/10.14734/PN.2019.30.3.134

Abstract

OBJECTIVE
This study aimed to find out the correlation between bilirubin levels and delivery methods in term babies with neonatal hyperbilirubinemia.
METHODS
This retrospective study was performed in a single center. The subjects were full-term neonates (37-41 weeks of gestational age) with a chief complaint of hyperbilirubinemia (serum total bilirubin ≥12 mg/dL) admitted to the Bundang Jesaeng General Hospital from May 2015 to July 2018. The subjects were divided into two groups according to delivery methods (vaginal delivery [VD] and cesarean section [CS]). Total bilirubin levels were compared between the two groups, and the correlation between severe hyperbilirubinemia (serum total bilirubin ≥25 mg/dL) and delivery methods was analyzed.
RESULTS
A total of 87 neonates were enrolled. Of 87 neonates, 59 (67.8%) were born by VD and 28 (32.2%) by CS. The mean serum total bilirubin level of the VD group was significantly higher than that of the CS group (21.5±4.0 mg/dL and 17.5±3.4 mg/dL, respectively; P<0.001). There were also significant differences in bilirubin levels according to delivery methods in subgroups based on demographic characteristics, except in cases when the age of neonates exceeded 7 days on admission and in breast-feeding neonates. In addition, VD was significantly correlated with an increased risk of severe hyperbilirubinemia (relative risk 1.5; 95% confidence interval 1.2-1.9; P=0.031).
CONCLUSION
This study showed that term neonates with hyperbilirubinemia born by VD had significantly higher bilirubin levels than those born by CS, and were also significantly correlated with severe hyperbilirubinemia.

Keyword

Hyperbilirubinemia, neonatal; Delivery, obstetric

MeSH Terms

Bilirubin*
Cesarean Section
Delivery, Obstetric
Female
Hospitals, General
Humans
Hyperbilirubinemia*
Hyperbilirubinemia, Neonatal
Infant, Newborn*
Methods*
Pregnancy
Retrospective Studies
Bilirubin

Reference

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